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So let’s say there is a supplement company selling a weight loss product that has ephedra in it. Ephedra, as you may know, was banned by the FDA in 2004 due to a high rate of serious side effects and ephedra-related deaths. Now let’s say that said supplement company, full well knowing the adverse health risk of ephedra, goes ahead to manufacture and sell this product to the public anyway. Should this company be held liable for any harm done to the public health? Should they be fined, punished, or shut down? What are the necessary measures to be taken to assure this doesn’t happen again?

If you believe that the supplement company acted out of negligence and greed, and compromised public health, then you probably also believe that the company should be punished to the full extent possible. Now what if it wasn’t a supplement company at all, but a pharmaceutical manufacturer instead. And let’s say the compound in question wasn’t ephedra but Paxil, the popular antidepressant, what would you say then?

Well that’s exactly what happened to ephedra–can anyone say Metabolife?–and it’s happening now with Paxil. In the Metabolife fiasco, Metabolife International Inc. the manufacturer of Metabolife 356, at its height a several hundred million dollar a year product, pled guilty to filing fraudulent tax returns and was sentenced to pay a criminal fine of $600,000, and more than a billion dollars in personal injury claims. Along with the banning of its most popular product, the monetary penalties buried the company which filed for bankruptcy in 2005.

So what will happen to GlaxoSmithKline PLC, makers of the mega best-selling antidepressant Paxil, which was the fifth-most prescribed antidepressant in the United States as early as 2006? A U.S. Department of Justice investigation is being conducted into whether the drug maker withheld data about the suicide risks of Paxil. Just another day at the office for antidepressant manufacturers. I’ve already reported on this and similar stories in earlier posts (and here, and here)–seems to be par the course with these massive money making meds. According to recent reports, the Justice Department is looking into GlaxoSmithKline’s marketing practices, pushing their product despite having information that the antidepressant increased the risk of suicidal tendencies in its takers.

So what will happen to GlaxoSmithKline? My guess, probably not much. They’ll fight the allegations professing the high road. They’ll lie and say they didn’t know about the risks. And when they eventually found out, they’ll say, they then took appropriate measures. I mean, what else could they possibly say? They’ll get slapped with a fine and warning. For a multi million dollar company like Metabolife that might cause ruin. But for a multi billion dollar company like Glaxo, well…it won’t do much. And I’m sure GlaxoSmithKline will be just fine. They’ll go on, business as usual.

This month on the Dr. Nick Show, I talk at length about lifestyle drugs. Lifestyle drugs are devised to treat conditions that fall outside the medical realm of illness. Take male pattern baldness for instance – medical illness or life circumstance? Oh well, we have drugs to treat it either way. Should insurance companies (read: insurance premium holders/consumers/you and me) have to pay for it?

Another way to define lifestyle drugs is: medicines that treat conditions caused by lifestyle choices. So, for instance, there are some groovy weight-loss drugs on the market right now. Cool. Should you rely on them solely? Hmmm. Or, should you pound the treadmill, pound the weights, and cut the calories? I mean, why should one do all that hard work when there’s this cool little pill? I dunno, why?

Well if you listen to the latest episode of the Dr. Nick Show, you’ll get all the details on lifestyle drugs, and you’ll be able to make a decision on your own. And no matter what, you’ll see how these drugs are defining the direction our culture is moving with regard to pharmaceutical science.

It’s no problem – it simply is what it is. However, just know that every substances comes with an added risk. And there just ain’t an easy answer – like a pill – that can fix all of our problems. The piper always gets paid in one way or another, ya know.
Anyway, lifestyle drugs are here to stay. It’s big business. Check out these booming numbersBusinessWeek calls them blockbusters (with sales of $1 billion or more a year). Drugs to help people wake and sleep as they please are particularly popular. And, of course, let’s not forget the drugs that help men have better erections.
No, no Campos – that’s help men who can’t have erections.
Uh, no…it’s not. Lot’s of young, healthy guys are partying on Viagra – Viagra and methamphetamine, that is. Or ecstasy. Or coke. Swear. Check it out . But don’t forget the risks gents. There’s always risks. For instance, the baldness drug propecia can cause birth defects if pregnant women inhale particles of broken pills (dosages are taken in half pills, so consumers must break them in half – brilliant, right?) or handle whole pills. And some cancer concerns exist with propecia too (scroll down to possible health concerns).
So, like I said, the lifestyle drugs are here to stay. Risk aside, the market is far too lucrative for pharmaceutical companies to slow down development. No to worry, just know the risks and be careful. Avoiding lifestyle drugs, in my opinion is always best, but, if ya gotta do ’em, then do ’em intelligently – which is, for a very short period of time.
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