Currently viewing the category: "brain cells"

How’s this for random and weird?  Three people have died this year from a brain-eating amoebaNaegleria fowleria microscopic organism found in warm fresh water like lakes, rivers, hot springs and soil.  The victims include a a 16-year-old Florida girl, who contracted the infection from swimming in a river, and a 9-year-old Virginia boy, who died a week after he went to a fishing day camp, and a 20-year-old man in Louisiana, who died after using a neti pot–a teapot-shaped device used to run salt water through the sinuses to relieve allergies, colds and sinus troubles.

N. fowleri usually enters the system through the nasal passages, very often from jumping or diving into water.  The amoeba then makes its way up to the brain where it digests brain cells, killing the person within two weeks.  The disease is called primary amebic meningoencephalitis, or “PAM.”

Although a harrowing fate for the inhaler, N. fowleri does not actively seek out human brains; it really is a bacteria-consuming parasite.  But, like all of us, it will consume what it can until it finds the meal of its choice–to the great misfortune of the human unlucky enough to inhale the microscopic blob.

This illness is extremely rare–only 120 reported U.S. cases (almost all of them deaths) since the amoeba was first identified in the early 1960s, according to the Centers for Disease Control and Prevention (CDC).  The annual incidence of infection (and thus deaths) is three per year.

Brain-eating amoebic infection seems to be confined to the south, where all three victims this year contracted it.  The neti pot case is especially weird, as the parasite tends to live in warmer waters.  It also brings up some useful precautions one should take at all times when swimming in fresh water lakes and rivers in the south, or when using a neti pot.

Lake and river swimmers should hold their nose shut or use nose clips to prevent water being forced up the nasal passages.  And neti pot users should always boil and sterilize the water before running it through the nasal passages.  By following the instructions on the package of the neti pot, users will be most safe.

It’s a tragedy for the families suffering the loss of their loved ones to something as random as an encounter with a rare amoeba.  But it should remind us all to take precautions.  I will admit, though, I probably wouldn’t have considered running into a brain-eating amoeba while filling my neti pot, either (although I also have no desire to use one of these–not against it, just not interested).

I think the most important thing is for people to be aware; so perhaps the CDC needs to make one of those public service announcements (PSAs) and show it as summer begins every year.  Saying that, we probably will still see three deaths a year.  N. fowleri probably hasn’t survived for this long without having a few tricks up its flagella.

Check this tripper: Scientist say that the central nervous system (CNS) can rewire itself to bypass damaged nerves that cause paralysis. Tiny nerves in the brain and spinal cord can actually crisscross creating new nerve pathways between brain cells and nerve cells that control movement. Injuries once thought to be irreversible now seem to show hope of recovery.

The study conducted at the University of California, Los Angeles looked at mice whose long axon nerve fibers were blocked causing paralysis of their hind legs. However, researchers left the core of the mice’s spinal cords, which contained short nerve fibers, intact. Within eight weeks the mice regained movement in their hind legs, astonishing researchers. The scientists then blocked the short nerve fibers, once again, causing hind leg paralysis. This showed that the short nerve fibers, which had reconnected, were responsible for the regain in hind leg movement.

Wow! Imagine that. Nerve cells repairing themselves and creating new connections in a self-healing, self-regulating repair process. I find this new discovery absolutely fascinating, although I’m not exactly surprised by it. I would expect this type of self-repair to be inherent in living organisms, especially one as complex as Homo sapien. And I’m certain we are just seeing the tip of the iceberg. I still contend that the greatest gains in human health and healing will be realized in the realm of mind-body dynamics in the future–and perhaps not as far in the future as one might think.

The implications go way beyond reversing paralysis, in my mind. I think that all healing probably follows this type of mechanism in one way or another. There is so much about the human body and it’s physiology that we do not know, especially on the molecular (and smaller) level. I’m excited to see where science will lead us tomorrow. The human mind and body are truly magnificent, and we have yet to realize their full potential. Truth is, we probably haven’t even seen the half of it.

New research shows that long-term memory storage is not as secure as once thought. In fact, it is now evident that memory can be erased. You heard me right. All those fond recollections of our youth can be whisked away forever by just blocking a protein that controls information flow between brain cells.

U.S. and Israeli researchers found these results by feeding rats saccharine, which made them sick, and then teaching the rats to associate the taste of saccharine with feeling ill. The scientists then injected the rats with an enzyme inhibitor called ZIP, blocking the protein PKMzeta, which controls memory. As a result, the rats were unable to remember the association with saccharine (feeling ill), regardless of how long they were trained. This suggests that a key mechanism in the brain works like a piece of machinery to store long-term memory. According to Yadin Dudai who led the study, “Long-term memory can be erased.”

This study is being touted as a breakthrough for the understanding and future treatment of dementia, a progressive decline of mental function well beyond that associated with normal aging. I certainly think that this is one potential use for these recent findings; however, I can’t help but feel a little creeped out by the possibility that we may be seeing the future with regard to some Orwellian “mind control”, a la Eternal Sunshine of the Spotless Mind. And it’s not lost on me that this study was conducted by two groups that could greatly benefit from a few erased memories in the world of politics and national security. Although I’m not usually one to subscribe to conspiracy theories, I still feel a bit uneasy about any research that leads to tampering with brain function. I mean, we think therefore we are, right? Oh well, I guess we’ve got to take the good with the bad with every situation, and that includes with science. Let’s just hope human trials won’t be taking place anytime soon.

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