Currently viewing the category: "magic bullets"

Just another very big reason to take care of your health while you still have it: Magic bullets don’t always work; and often, they can turn deadly. Take for instance the latest news coming out of the 60 Minutes newsroom. In an interview to be aired next Sunday, a medical researcher has disclosed that 22,000 lives were lost due to complications of a drug used to stem bleeding during open heart surgeries.

According to researcher Dr. Dennis Mangano, an observational study he conducted showed that the drug Trasylol, manufactured by Bayer AG, was linked to kidney failure and death. The scary part is that Trasylol, one of the most widely-used drugs of its kind, was used on one-third of all open heart surgeries during the drug’s “height”. Worse yet, in his study, Dr. Mangano recommended discontinuing the use of Trasylol and that the drug be recalled. Doh!

But wait, it gets better: Bayer, the German pharmaceutical company, well-known for its aspirin, also knew of the link between Trasylol and kidney disease…but withheld the information from the FDA. Nice. Cha-Ching!

Once again, just another big reason to take care of your health now. Your heart needs proper caring and maintenance–through diet and exercise–just like all your organs do. Yeah, I know we all know this–but is everyone doing what they need to do in order to keep their hearts ticking? If you’re not, then you’re flirting with disaster. Just imagine going in for a heart bypass and coming out with dialysis. The major point here is that nobody is going to care for your health as much as you do. Period. Some companies will have no remorse to make money at the expense of your safety–you’d better believe it. So if you don’t care for your heart like its your most valuable asset, then don’t expect anybody else to, either–not Bayer; not your surgeon; not your insurance agent; not your Congressman; not your next President, no matter who that might be; not anyone. You’d better believe that.

One of the first things doctors learn in rudimentary physiology class is that, when it comes to preventing heart disease, high HDL or “good” cholesterol is more important than low LDL or “bad” cholesterol. In fact, HDL levels are four times greater than LDL levels in their ability to predict the development of coronary atherosclerosis. Basic, basic, basic physiology.

But an interesting thing happens between doctor school and practicing–it’s called influence from the outside world. In the case of doctors, that influence often comes from pharmaceutical industry. C’mon Campos, not another evil pharmaceutical industry story (hey, I haven’t written one yet, please). No, no–it’s more like another example of how we’ve come to worship outside factors when it comes to our health. Check this one out.

Recent research published in the New England Journal of Medicine shows that no matter how much bad cholesterol is lowered in the blood, it’s the amount of good cholesterol that still reigns supreme. Yes, the concentration of your HDLs (high density lipoproteins) plays a vital part in preventing cardiovascular diseases, like heart attacks and strokes.

Yeah, so? Well if you haven’t heard yet, those hyper-pedastalized miracle drugs known as statins are some of the most prescribed drugs of our day. Statins work by lowering LDL (low density lipoproteins) levels in the blood, and this, it has been promised, will lower our risk of heart disease. Great! Prescribe them like crazy. People don’t work out. People don’t eat right. Who cares? Give ’em statins. You’ve got boderline high cholesterol. Statins. You’re almost diabetic? Statins. You’ve seen the cholesterol commercial and you’re concerned? Statins.

Statins. Statins. Statins.

Well I’ve got news for you. You want to lower your risk of cardiovasular disease? You’ve got to watch what you eat and work out, period. Oh yeah…it’ll help if you quit smoking too, but how about just starting with exercise? You see, I’ve got a real problem with the idea of looking for magic bullets. They are illusions, people–ILLUSIONS! They give false security and false hopes. Nothing in life is free. You’ve got to work for everything. Exercise. Diet. That’s the real answer. Not statins.

OK, I’ll be fair. For people who have dangerously high levels of LDLs–if I was their MD–I’d give them statins for a very brief period, and I’d absolutely prescribe heavy doses of lifestyle management (read: nutrition and exercise). But I wouldn’t perscribe statins for people with boderline normal cholesterol levels as some Dr. Idiots are recommending (also read this–effin’ scary).

According to Dr. Philip Barter of the Heart Research Institute in Sydney, one of the lead authors of the study, “Even when LDL is taken down to very low levels, the kind of levels people say should be the aggressive targets, having a low HDL is still associated with a substantial increase in risk. (emphasis mine)” So, basically, you’ve got to work to bring your HDL levels up to par. And here’s the beauty: It’s the ratio of total cholesterol to HDL that really matters (see this brilliant explanation here), where total cholesterol = HDL+LDL. Therefore, HDL+LDL/HDL. So, if you bring up your HDL levels, you don’t need statins. Duh.

OK, here’s how you can raise your HDL levels–exercise regularly, eat wholesome foods, take essential fatty acids, and moderate your smoking and drinking habits. And you can naturally decrease your LDL levels by decreasing saturated fat intake, maintaining good body composition, increasing dietary fiber, and increasing aerobic exercise. Booyah!

But wait…fugdat. Ain’t there a drug I can take, Homey?

Sure Pfizer is working on one. It’s called torcetrapib. Oh wait. It killed people in a large drug trial. Oh well–I guess you’ve gotta work out. Says Barter again: The alternative is to “become lean and become very active. That’s probably as effective as anything we have at the moment. But most people who try don’t succeed,” Barter said. “The biggest frustration is that we don’t have the magic bullet like we do for the LDL.”

Ah yes, the ‘ol magic bullet. Well, keep looking–it’s your time, your money, and your health. If you want to believe, then be my guest. But I’ll just be over here dancing with the Tooth Fairy.

Copyright © 2013 Dr. Nick Campos - All Rights Reserved.